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Press Releases
December 18, 2009 Successful Completion of Major Portions of PMX 30063 Phase IB Clinical Trial

Study Demonstrates That PMX-30063 May Be Safely Given In Multiple Doses
December 09, 2009 PolyMedix to Host Webcast on Heparin, Bleeding Complications, and PolyMedix’s PMX-60056 Reversing Agent Tuesday, December 15, 2009 at 10:00am-EST

December 07, 2009 Data on PolyMedix’s Heptagonist Compounds to be Presented at Annual Meeting of the American Society of Hematology

Meeting in New Orleans, Louisiana, December 5-9, 2009
November 17, 2009 PolyMedix Completes $20.7 Million Equity Financing

Funds To Be Used To Continue Development of Two Drug Candidates Into Phase 2 Human Clinical Trials
November 11, 2009 PolyMedix Announces Up To $21 Million Public Equity Offering

Funds To Be Used To Continue Development of Two Drug Candidates Into Phase 2 Human Clinical Trials
October 27, 2009 POLYMEDIX COMPLETES SUCCESSFUL PHASE 1B CLINICAL STUDY OF HEPARIN ANTAGONIST PMX-60056

PMX-60056 Heptagonist Meets Safety and Efficacy Endpoints in Reversing Effects of Heparin
September 29, 2009 PolyMedix Initiates Dosing in Phase 1B Clinical Studyof Novel Anticoagulant Antagonist Compound

PMX-60056 Heptagonist Reversing Agent for Heparin and Low Molecular Weight Heparins
September 28, 2009 PolyMedix Receives U.S. Patent Protection for Licensed Computational Methods to Design Antimicrobial Polymers
September 14, 2009 POLYMEDIX TO MAKE THREE PRESENTATIONS OF ANTIBIOTIC DATA AT THE 49th ANNUAL INTERSCIENCE CONFERENCE ON ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (ICAAC)

Annual Meeting on Behalf of the American Society of Microbiology (ASM) San Francisco, CA, September 12 - 15, 2009
August 27, 2009 POLYMEDIX AND UNIVERSITY OF MASSACHUSETTS RECEIVE $100,000 CONTRACT TO DEVELOP NOVEL ANTIBACTERIAL COMPOUNDS AGAINST DRUG-RESISTANT BACTERIAL BIOFILMS

Contract Supported by the U.S. Army Research Office
July 27, 2009 POLYMEDIX AND UNIVERSITY OF MASSACHUSETTS AMHERST RECEIVE UP TO $6.6 MILLION NIH GRANT TO DEVELOP NEW ANTIBIOTICS

Project to develop new defensin-mimetic antimicrobial compounds for biodefense and emerging food-borne infectious diseases
PolyMedix to receive up to $3.5 million in funding over 5 years

July 23, 2009 POLYMEDIX AND UNIVERSITY OF MASSACHUSETTS RECEIVE UP TO $100,000 CONTRACT TO DEVELOP NOVEL ANTIBACTERIAL COMPOUNDS AGAINST PATHOGENS OF MILITARY INTEREST

Contract Supported by the Office of Naval Research
July 17, 2009 PolyMedix To Present At
5th International AIDS Society (IAS) Conference

Cape Town, South Africa July
19 - 22, 2009

July 17, 2009 Data on PolyMedix Heptagonist Compounds Presented At The International Society on Thrombosis and Hemostasis (ISTH) Conference
July 15, 2009 PolyMedix Receives United States Patent For Angiogenesis Inhibitor Compounds

Potential New Therapeutic Treatments for Many Diseases, Including Age-Related Macular Degeneration
June 02, 2009 POLYMEDIX APPOINTS DOUGLAS J. SWIRSKY TO BOARD OF DIRECTORS
June 12, 2009 POLYMEDIX RECEIVES $923,000 SBIR GRANT TO SUPPORT DEVELOPMENT OF LMWH ANTAGONISTS

Grant Represents Eighth Outside Grant or Research Supported Funding
June 05, 2009 PolyMedix Initiates Dosing in Second Phase I Clinical Study of Novel Systemic Antibiotic Compound

PMX-30063 Phase IB Clinical Study Follows the Successful Completion of the Phase IA Clinical Study
June 04, 2009 PolyMedix to Present at Noble Financial Capital Markets 25th Anniversary Fifth Annual Emerging Growth Equity Conference June 8, 2009

Seminole Hotel, Hollywood, Florida, June 8-9, 2009
June 02, 2009 POLYMEDIX RECEIVES $1.6 MILLION CONTRACT FROM THE DEFENSE THREAT REDUCTION AGENCY (DTRA) TO DEVELOP ANTIBIOTIC COMPOUNDS TO COMBAT BIOWARFARE PATHOGENS

Goal To Devise More Effective Rapid-Response Countermeasures
May 21, 2009 PolyMedix Receives Regulatory Clearance to Initiate Second Phase I Clinical Study of Novel Systemic Antibiotic Compound

Phase IB Clinical Study Follows the Successful Completion Of the Phase IA Clinical Study
May 20, 2009 POLYMEDIX SECURES $10 MILLION EQUITY LINE FACILITY WITH DUTCHESS EQUITY FUND, LP

PolyMedix to Receive up to $10.0 Million Over Three Years
May 18, 2009 PolyMedix, Inc. To Present At American Society of Microbiology 109th General Meeting

May 17-21, Philadelphia, PA
May 06, 2009 PolyMedix To Present At
22nd International Conference on Antiviral Research (ICAR)

Miami Beach Resort & Spa, Miami, Florida, USA
May 3rd - May 7th, 2009

April 30, 2009 PolyMedix Presents Anti-tuberculosis Data At
5th European Conference on Clinical and Social Research on AIDS and Drugs

28 - 30 April 2009
Vilnius, Lithuania

March 23, 2009 Antimalaria Data on PolyMedix Antimicrobial Compounds
Presented at Malaria Keystone Conference

March 22nd to 26th, 2009
Breckenridge, Colorado

March 18, 2009 PolyMedix To Present At
SMi Superbugs & Superdrugs Conference - A Focus on Antibacterials

March 18-19, 2009,
Crowne Plaza Hotel - London St James, London, United Kingdom

March 17, 2009 PolyMedix To Present At Healthtech Drug Development Conference: The Challenge of Antibacterial Drug Development

March 18th to 19th, 2009 Hilton San Diego, San Diego, California
March 11, 2009 POLYMEDIX COMPLETES FIRST-IN-MAN PHASE I CLINICAL STUDY WITH NOVEL HEPARIN ANTAGONIST PMX-60056

Clinical Proof-Of-Concept Study Expected To Follow
March 10, 2009 PolyMedix’s CEO to Present at
Boston UNCommon
Noble Financial Capital Markets
March 12, 2009
Seventeen Selected Portfolio Companies
March 04, 2009 PolyMedix To Present At
The 2009 Gordon Conference on Antimicrobial Peptides
March 1-6, 2009, Ventura, CA
February 17, 2009 PolyMedix’s CEO to Present at Roth Capital 21st Annual Growth Stock Conference on February 17, 2009

This press release contains forward-looking statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995 that involve risks, uncertainties and assumptions that could cause PolyMedix’s actual results and experience to differ materially from anticipated results and expectations expressed in these forward looking statements. PolyMedix has in some cases identified forward-looking statements by using words such as “anticipates,” “believes,” “hopes,” “estimates,” “looks,” “expects,” “plans,” “intends,” “goal,” “potential,” “may,” “suggest,” and similar expressions. Among other factors that could cause actual results to differ materially from those expressed in forward-looking statements, PolyMedix’s compounds may not enter or successfully complete clinical testing, or be granted regulatory approval to be sold and marketed in the United States or elsewhere. A more complete description of these risk factors is included in PolyMedix’s filings with the Securities and Exchange Commission. You should not place undue reliance on any forward-looking statements. PolyMedix undertakes no obligation to release publicly the results of any revisions to any such forwardlooking statements that may be made to reflect events or circumstances after the date of this press release or to reflect the occurrence of unanticipated events, except as required by applicable law or regulation.

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© 2009 PolyMedix, Inc.